Familial Mediterranean Fever in older children
نویسندگان
چکیده
Results The study group comprised 317 FMF patients (170 females, 147 males) with a mean age of 12.2 ± 5.7 years. There were 267 patients (84.3%) in group I and 50 patients (15.7%) in Group II. Median attack frequency before colchicine therapy was 24/year in Group I and 12/year in Group II (p<0,05). Although the frequency of majority of the clinical features did not differ between the groups, fever was seen less frequently in Group II patients (p=0,003). M694V homozygosity was also less frequently detected in group II patients (p=0.022). Median disesase severity scores and final colchicine dosages were lower in Group II (p<0,001; p=0,003). Median delay in diagnosis was 24 months in Group I and 12 months in Group II (p=0,002).
منابع مشابه
Familial Mediterranean Fever: Review of Literature and Report of Two Cases
Familial Mediterranean fever, an autosomal recessive disorder, is a member of the periodic fever syndromes, and considered to be the most common cause of recurrent febrile episodes in children. It is important to understand the disorder as familial Mediterranean fever falls on a spectrum of various presentations; the recurrent episodes of familial Mediterranean fever may be so severe that the q...
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